MOLECULAR CHARACTERIZATION OF CANINE DISTEMPER VIRUS
Thursday, June 2, 2016, 4:15 PM – 4:45 PM
Czarina Kristine D. Nobleza1, Maria Rosario S. Racho2 and Dennis V. Umali1
1 Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of the Philippines Los Baños, College, Laguna, Philippines
2 Veterinary Teaching Hospital, Diliman Station, College of Veterinary Medicine, University of the Philippines Los Baños, College, Laguna, Philippines
Canine distemper (CD) is a highly infectious viral disease caused by the Canine distemper virus from the genus Morbillivirus, under the family Paramyxoviridae. CDV has been reported to infect all species of terrestrial carnivores worldwide, namely Canidae (fox, dingo, coyote, wolf, jackal); Mustelidae (ferret, mink, weasel, marten, skunk, badger, otter); Procyonidae (raccoon, kinkajou, coati), Felidae (cheetah, lion, jaguar, margay, ocelot), Ailuridae (red panda), Hyaenidae (hyena), Ursunidae (bear), and Viverridae (palm civet). Given the extent of susceptible species and seriousness of its clinical signs, it is critical to gain more insight about the factors involved in its transmission and epidemiology in order to search for therapeutic strategies that will solve or prevent any future outbreak in the country. In this study, a local CDV strain was characterized molecularly to identify its genetic characteristics. Phylogenetic analyses were also performed to infer on possible transmission routes of the virus. At present, this is the first study to genetically characterize CDV in the Philippines.